Importin β Negatively Regulates Nuclear Membrane Fusion and Nuclear Pore Complex Assembly
نویسندگان
چکیده
منابع مشابه
Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly.
Assembly of a eukaryotic nucleus involves three distinct events: membrane recruitment, fusion to form a double nuclear membrane, and nuclear pore complex (NPC) assembly. We report that importin beta negatively regulates two of these events, membrane fusion and NPC assembly. When excess importin beta is added to a full Xenopus nuclear reconstitution reaction, vesicles are recruited to chromatin ...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2003
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e03-05-0275